Abstract：Objective To study and evaluate the short-term effect and safety of laparoscopic radical total gastrectomy in the treatment of upper gastric cancer.Methods60 patients with upper gastric cancer were selected in our hospital from January 2014 to June 2017 were randomly divided into observation group and control group according to random number table method.30 cases in each group.In the control group,radical gastrectomy by traditional laparotomy was used,while in the observation group,laparoscopic total gastrectomy was performed.The number of lymph node dissection,operative conditions,postoperative pain score,postoperative recovery time,incidence of complications and immune function were compared between the two groups.Results There was no significant difference in operative time between the two groups(P＞0.05).However,the number of lymph node dissection in the observation group was more than that in the control group(P＜0.05).The intraoperative blood loss was less than that in the control group(P＜0.05).Pain scores in the observation group were lower than those in the control group at 8,12,24 and 48 h after operation(P＜0.05).The indexes of postoperative exhaust recovery time,time of being off bed independently,time to consume liquid food,and hospital stay,etc.in the observation group were shorter than those in the control group(P＜0.05).The total incidence of postoperative complications in the observation group was 3.33%,while that in the control group was 20.00%which differed significantly(P＜0.05).The indexes of immune function in the control group after operation were all lower than those before operation,the differences were statistically significant(P＜0.05).While those in the observation group were not statistically significant before and after operation(P＞0.05).Conclusion Laparoscopic radical total gastrectomy for the treatment of upper gastric cancer can alleviate the surgical trauma,postoperative pain and immune impairment,reduce postoperative complications,promote postoperative recovery,and effectively clear lymphatic nodes with a significant short-term effect.
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