摘要目的探讨氟比洛芬酯联合舒芬太尼用于腹腔镜全宫切除术术后镇痛的效果。方法选取我院2015年5月～2016年7月行腹腔镜全宫切除术患者200例，随机分为研究组与对照组，每组100例。对照组患者术后给予舒芬太尼、氟哌利多镇痛，研究组患者在对照组基础上加用氟比洛芬酯镇痛。采用视觉模拟评分（VAS）对两组患者术后 1、4、8、16、24、48 h 镇痛情况进行评分，并观察不良反应发生情况。结果研究组患者术后 1、4、8、16、24、48 h 的VAS评分显著低于对照组，差异有统计学意义（P＜0.05）。研究组患者的头晕、皮肤瘙痒、呼吸抑制、恶心呕吐和消化道溃疡等不良反应发生率显著低于对照组，差异有统计学意义（P＜0.05）。结论氟比洛芬酯联合舒芬太尼用于腹腔镜全宫切除术术后镇痛效果显著，不良反应少，值得临床推广应用。
Abstract：ObjectiveTo investigate the effect of Flurbiprofen Axetil combined with Sufentanil on postoperative analgesia in laparoscopic total hysterectomy.MethodsA total of 200 patients with laparoscopic total hysterectomy in our hospital from May 2015 to July 2016 were selected as research objects.All of the patients were randomly divided into the study group and the control group,with 100 cases in each group.Patients in the control group were given Sufentanil and Droperidol analgesia,and the patients in the study group were treated with Flurbiprofen Axetil on the basis of the control group.The visual analogue scale (VAS)of the two groups were evaluated at 1,4,8,16,24,48 h,and the adverse reactions were observed.ResultsThe VAS scores of the study group at 1,4,8,16,24,48 h were significantly lower than those in the control group,with significant difference (P＜0.05).The incidence of adverse reactions such as dizziness,pruritus,respiratory depression,nausea,vomiting and gastrointestinal ulcer in the study group were significantly lower than those in the control group,the difference was statistically significant(P＜0.05).ConclusionFlurbiprofen Axetil combined with Sufentanil for postoperative analgesia in laparoscopic total hysterectomy is effective and less adverse reactions,so it is worthy of clinical promotion and application.
叶三春. 氟比洛芬酯联合舒芬太尼用于腹腔镜全宫切除术术后镇痛的效果[J]. 中国当代医药, 2018, 25(5): 110-112.
YE San-chun. Effect of Flurbiprofen Axetil combined with Sufentanil on postoperative analgesia in laparoscopic total hysterectomy. 中国当代医药, 2018, 25(5): 110-112.
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