Abstract：ObjectiveTo investigate the application effect of nitrous oxide(N2O)inhalation in photodynamic therapy for condyloma acuminata.MethodsFrom June 2016 to June 2017,128 patients with condyloma acuminata who were treated by photodynamic therapy in our hospital were enrolled as research objects.According to different therapeutic methods,they were divided into the N2O group (n=60)and the Tramadol group (n=68).The NRS pain scores during and after surgery,and adverse drug reactions were compared between the two groups.ResultsIn the N2O group,the analgesic effect by inhalation of N2O was greatly better than that of oral administration of the Tramadol group (P＜0.01).The vital signs were stable in the process of surgery and after surgery in both groups.The overall incidence of adverse events in the N2O group was 13.33%,and 11.76%in the Tramadol group,without a significant difference after comparison between the two groups(P＞0.05).ConclusionN2O inhalation can effectively alleviate the pain in the treatment of condyloma acuminatum by photodynamic therapy in high drug safety.
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