Abstract:ObjectiveTo investigate the clinical value of serum procaicitonin (PCT)in the early diagnosis and evaluation of curative effect for the patients with peritoneal dialysis (PD)-related peritonitis.M ethods60 patients receiving PD in the center of PD in our hospital from October 2015 to October 2016 were selected.According to whether PD related infection occurred,the patients were divided into the infection group (30 cases)and the non-infection group(30 cases).Another 30 healthy subjectswere selected as the control group.The white blood cell count(WBC),C-reactive protein (CRP)and PCT concentration were tested in the three groups.The changes of the above indicators in the patients with PD-related peritonitis before and after the treatmentwere dynamically observed,and the relationships between PCT and CRP,WBC were analyzed.ResultsCompared with the non infection group PD patients and the healthy control group,the serum PCT level of the infection group was significantly higher,the difference was statistically significant(P<0.05).Compared with the healthy control group,the levels of serum CRP in the non-infection group and the infection group were significantly higher,the difference was statistically significant(P<0.05).There was no statistically significant difference in the level of white blood cells between the three groups (P>0.05).After the anti-infection treatment,there was statistically significant differences in serum PCT and CRP in the PD patients in the infection group before and after the treatment(P<0.05),and therewas no change ofWBC before and after the treatment(P>0.05).There was a positive correlation between serum PCT and CRP (P<0.05).ConclusionSerum PCT can be used as an early sensitive index for the diagnosis of PD-related peritonitis and judgment of its efficacy.
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