Abstract：Objective To evaluate the application value of the C-reactive protein(CRP)level in predicting spontaneous stone passage in patients with 5 to 9 mm distal ureteral stones.Methods Clinical data of patients with distal ureteral stones who met the inclusion criteria from December 2014 to December 2015 were collected.CRP levels were measured.After 5 weeks,according to whether the spontaneous stone passage,the patients were divided into the stone discharging group and the stone undischarged group.The receiver operating characteristic(ROC)curve was drawn to determine the optimal cut-off values of CRP for predicting spontaneous stone passage.Results A total of 348 patients completed the study.Spontaneous stone passage was observed in 224 patients,the stone discharging rate was 53.8%.ROC analysis resulted in an area under the curve of 0.882 for serum CRP.Using ROC,a cut-off point of 8.5 mg/L for CRP yieldedappearedoptimalforpredictionofspontaneousuretericstoneexpulsion(sensitivitywas76.6%,specificitywas 86.2%).In the proportion of CRP＞8.5 mg/L,the stone undischarged group was significantly higher than that the stone discharging group,with significant statistical difference(P＜0.05).In the stone discharging group,time to spontaneous stone passage in patients with a CRP level less than or equal to 8.5 mg/L was shorter than that the CRP Level over 8.5 mg/L,the number of episodes of pain and the visual analogue scale(VAS)score were significantly less than that with a CRP level over 8.5 mg/L(P＜0.05).Conclusion CRP levels is useful for predicting.When CRP levels are greater than 8.5 mg/L,move aggressive interventions techniques should be considered.
李飞杨;吕建林. C反应蛋白预测远端输尿管结石自排的应用价值[J]. 中国当代医药, 2017, 24(28): 79-82.
LI Fei-yang;LV Jian-lin. Application value of C-reactive protein level in predicting spontaneous stone passage in patients with distal ureteral stones. 中国当代医药, 2017, 24(28): 79-82.
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