Abstract:ObjectiveTo evaluate the application effect of Amlodipine combined with Atorvastatin Calcium in the treatment of patients with hypertension and hyperlipidemia.Methods120 elderly patients with hypertension and dyslipidemia treated in our hospital from May 2015 to May 2016 were selected and were randomly divided into two groups with 60 cases in each group.The patients in the control group were only treated with Amlodipine while the patients in the observation group were treated with Atorvastatin Calcium based on the treatment of the control group.Treatment effect and the incidence rate of adverse reaction occurred during treatment between two groups were compared.ResultsAfter treatment,systolic blood pressure(SBP)and diastolic pressure(DBP)were significantly decreased in the two groups(P<0.05),and those in the observation group were significantly lower than those of the control group(P<0.05).After treatment,the total cholesterol(TC),triglyceride(TG),low density lipoprotein(LDL-C)and high density lipoprotein(HDL-C)of the patients in two groups were significantly improved(P<0.05),and those in the observation group were improved better than those in the control group(P<0.05).The total effective rate of the observation group was 93.33%,while that of the control group was 80.00%and the curative effect in the observation group was better than that of the control group(P<0.05).The incidence of adverse reactions was 0.03%in the observation group while that was 0.05%in the control group,but the difference was not statistically significant(P>0.05).ConclusionThe pesticide effectof Amlodipine combined with Atorvastatin Calcium is obviously better than the single use of Amlodipine.Combined drugs can effectively achieve the effect of lipid-lowering and lowering blood pressure.This treatment has high safety and a high clinical value.
金伟. 氨氯地平联用阿托伐他汀钙在高血压伴高血脂中的应用评价[J]. 中国当代医药, 2017, 24(16): 51-53.
JIN Wei. Application evaluation of Amlodipine combined with Atorvastatin Calcium in the treatment of hypertension with hyperlipemia. 中国当代医药, 2017, 24(16): 51-53.