Abstract：ObjectiveTo analyze the clinical effect of Amlodipine Atorvastatin Calcium Tablets treating hypertension complicated with coronary heart disease.Methods108 patients with hypertension complicated with coronary heart disease treated by our hospital from July 2015 to July 2016 were selected as objects,and they were randomly divided into two groups,each group had 54 cases.The control group was given Extended Release Tablets of Nifedipine,while the observation group was given Amlodipine Besylate and Atorvastatin Calcium Tablets,after 2 months,blood lipid indexes, clinical effect 1 and 2 months of treatment,inflammatory indexes and adverse reactions after treatment between two groups were compared.ResultsCompared with the control group,LDL-C,TG,TC value was lower and HDL-C value was higher after treatment in the observation group (P＜0.05).After treatment,the IL-6,vWF,NO,ET index in the observation group compared with the control group was statistically significant(P＜0.05),it had no statistically significant differences in the level of CRP and TNF-α (P＞0.05).The total effective rate of the observation group was higher than that of the control group(P＜0.05).There was no significant difference in the incidence rate of adverse reactions between two groups (P＞0.05).ConclusionAmlodipine Besylate and Atorvastatin Calcium Tablets treating hypertension complicated with coronary heart disease can achieve a relatively significant clinical effect,and it can lower blood lipid,eliminate inflammatory factors with high safety,and it is worthy of further promotion.
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