Abstract:Objective To investigate the feasibility of Scopolamine combined with Dexamethasone acute toxic pulmonary edema and influence of symptoms disappear time.M ethods 72 patients with ATPE given emergency treatment in our hospital from January 2012 to June 2016 were selected and they were randomly divided into the control group and the observation group,there were 36 cases in each group.The control group was treated with 5~10 mg Dexamethasone every time,the total dose in 24 h was 15~30mg and the observation group was treated with Scopolamine(intravenous infusion of 1~3 mg,15~30 min)combined with Dexamethasone.The treatment effect,symptom disappearance time and complication of the two groups were compared.Results The drug onset time and pulmonary edema disappearance time of the observation group were significantly shorter than those of the control group(P<0.05).The cure rate of the observation group was significantly higher than that of the control group(91.67%vs 69.44%,P<0.05),and the complication rate was significantly lower than the control group(5.56%vs 22.22%,P<0.05).There was no significant difference in mortality between two groups(P>0.05).Conclusion Scopolamine combined with Dexamethasone can effectively improve the cure rate of ATPE,with the characteristics of rapid onset,fast symptoms,less complications and so on,the higher the value of clinical application.
钟建华. 东莨菪碱和地塞米松联合抢救急性中毒性肺水肿的可行性及对症状消失时间的影响[J]. 中国当代医药, 2016, 23(32): 38-40.
ZHONG Jian-hua. The feasibility of Scopolam ine combined w ith Dexamethasone acute toxic pulmonary edema and influence of sym ptom s disappear time. 中国当代医药, 2016, 23(32): 38-40.
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