Abstract：Objective To exp1ore the inf1uence of intravesica1 prostatic protrusion（IPP）on app1ication of α-b1ocker treated for patients with benign prostatic hyperp1asia（BPH）.Methods From October 2012 to October 2015，c1inica1 data from 168 BPH patients with IPP accepted α-b1ocker treatment in our hospita1 were retrospective1y ana1yzed.According to degree of IPP，they were divided into significant IPP group（IPP＞5 mm，n=63）and non-significant IPP group（IPP≤5mm，n=105）.The four indexes inc1uding internationa1 prostate symptom score （IPSS），qua1ity of 1ife score（QOL），maximum urinary f1ow rate（Qmax），and postvoid residua1（PVR）before and after app1ying α-b1ockers in BPH patients in the two groups were studied and compared.Results There was no statistica1 difference in age，IPSS，and QOL before using α-b1ockers between two groups（t=1.542，1.893，0.431，P＞0.05）.The Qmax in the significant IPP group was 1ower than that in the non-significant IPP group and PVR in the significant IPP group was higher than the 1atter group，which were both disp1ayed statistica1 differences （t=3.187，2.183，P＜0.05）.Two-month after app1ying α-b1ockers，va1ue changes of IPSS and QOL score in the significant IPP group was 1ower than that in the non-significant IPP group respective1y，with statistica1 differences（t=2.799，5.116，P＜0.05）.There was no great difference in changes of Qmax or PVR（t=1.919，0.852，P＞0.05）.Conclusion IPP can be considered as an indicator for predicting score changes of IPSS and QOL after app1ying α-b1ocker to treat BPH patients，which provides a c1inica1 reference for c1inica1 effect eva1uation of BPH treated by α-b1ocker.
叶木石； 李卓； 颜赟坤. 前列腺突入膀胱程度对前列腺增生患者应用α-受体阻滞剂治疗的影响[J]. 中国当代医药, 2016, 23(13): 57-59转63.
YE Mu-shi；LI Zhuo； YAN Yun-kun. Influence of intravesical Prostatic Protrusion on aPPlication of α-blocker treated for Patients with benign Prostatic hyPerPlasia. 中国当代医药, 2016, 23(13): 57-59转63.
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