Clinical observation of Yishen Huayu Paizhuo Decoction combined with Compound α-Ketoacid Tablets on treating chronic renal failure
PENG Yong1 ZHOU Xia2
1.Department of Nephropathy and Rheumatology of Traditional Chinese Medicine,Xiangya Pingkuang Cooperative Hospital(Pingkuang General Hospital)of Pingxiang City in Jiangxi Province,Pingxiang 337000,China;
2.Operating Room,Traditional Chinese Medicine Hospital of Pingxiang City in Jiangxi Province,Pingxiang 337000,China
Abstract：ObjectiveTo explore the clinical effect of Yishen Huayu Paizhuo Decoction combined with compound α-ketoacid tablets in the treatment of chronic renal failure (CRF).MethodsA total of 66 CRF patients treated in our hospital from July 2013 to June 2016 were selected and randomly divided into the medication-only group and the combined group,33 cases in each group.The symptomatic supportive treatment was provided in the two groups.In the medicationonly group,Compound α-Ketoacid Tablets was used,while in the combined group,on the basis of the medication-only group,Yishen Huayu Paizhuo Decoction was added.The indicators of renal function and nutrition indicators in the two groups were compared.ResultsThe levels of serum urea nitrogen,serum creatinine,and endogenous creatinine clearance in the two groups after treatment were lower than that before treatment,the levels of serum urea nitrogen,serum creatinine,and endogenous creatinine clearance in the combined group after treatment was lower than that in the medicationonly group,with significant difference (P＜0.05).The nutrition indicators including body weight,arm muscle circumference,thickness of skin-fold of musculus triceps brachii,hemoglobin,and serum albumin in the two groups after treatment were better than that before treatment,the nutrition indicators including body weight,arm muscle circumference,thickness of skin-fold of musculus triceps brachii,hemoglobin,and serum albumin in the combined group after treatment were better than that in the medication-only group,with significant difference (P＜0.05).ConclusionFor CRF patients,application of Yishen Huayu Paizhuo Decoction combined with Compound α-Ketoacid Tablets can not only improve patient′s renal function,but also better their nutritional status.
Toshihiro K，Yuriko M，Toshihiko O，et al.Exploration of novel predictive markers in rat plasma of the early stages of chronic renal failure[J].Anal Bioanal Chem，2014，406（5）：1365-1376.
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