Abstract：Objective To observe the changes of thyroid hormones in different levels in pediatric patients suffering from congenital heart disease（CHD）combined with cardiac failure due to pneumonia，and to probe into the correlations between thyroid hormones levels in different cardiac functional grading and cardiac function. Methods From 2012 to 2014，112 pediatric patients suffering from CHD with cardiac failure due to pneumonia in our department were selected as research objects and were set as congenital heart disease complicated with pneumonia and heart failure group.They were divided into mild，moderate，and severe cardiac failure groups based on modified Ross standard evaluation method. Forty-eight healthy children in the same period after physical examinations were classified into control group.The levels of thyroid hormones among groups and correlations between different levels of thyroid hormones and cardiac functions were compared. Results In CHD with cardiac failure due to pneumonia，there were changes in thyroid hormones levels，like decrease of T3，FT3，FT4，which were displayed statistical differences in the control group（P＜0.01）.With the severity of cardiac insufficiency，the decreases in T3and FT3were more significant.The severity of cardiac insufficiency was in a negative correlation between changes of T3（r=-0.562）. Conclusion Dynamic observation of serum thyroid hormones changes in children suffering from CHD with cardiac failure can be considered as a new objective index on disease severity and prognosis，which plays an important clinical significance on improving its prognosis，growth and development，and metabolic balance.
曲瑛琦. 甲状腺激素与儿童先天性心脏病合并肺炎心力衰竭的相关性研究[J]. 中国当代医药, 2016, 23(11): 92-94.
QU Ying-qi. Correlation study between thyroid hormones and congenital heart disease combined with cardiac failure due to Pneumonia in children. 中国当代医药, 2016, 23(11): 92-94.
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