静脉输注右美托咪定在小儿全凭静脉麻醉术后躁动的应用效果

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摘要目的观察右美托咪定对小儿全凭静脉麻醉下扁桃体和腺样体摘除术后躁动的影响。方法选取2014年2月～2016年2月门头沟区医院全凭静脉麻醉下行扁桃体和腺样体手术的60例患儿作为研究对象。采用随机数字表法将其分为右美托咪定组（n=30）与对照组（n=30）。右美托咪定组患儿麻醉前泵入右美托咪定0.5μg/（kg·h），对照组患儿采用持续泵注生理盐水的方法。记录两组患儿的麻醉时间和恢复时间。比较两组患儿恢复时及恢复后15、30min的小儿术后疼痛量表（CHIPPS）评分和小儿术后躁动量表（PAED）评分。同时观察比较两组患儿的恶心呕吐发生情况，并记录两组患儿CHIPPS评分＞3分和PAED评分＞12分的发生率。结果右美托咪定组患儿于恢复时及恢复后15、30min的CHIPPS评分低于对照组，差异有统计学意义（P＜0.05）；右美托咪定组患儿恢复时及恢复后15、30min的PEAD评分低于对照组，差异有统计学意义（P＜0.05）。两组患儿的麻醉时间、苏醒期恶心呕吐发生率、CHIPPS评分＞3分发生率、PAED评分＞12分发生率比较，差异无统计学意义（P＞0.05）；右美托咪定组患儿的恢复时间长于对照组，差异有统计学意义（P＜0.05）。结论静脉输注右美托咪定可降低小儿全凭静脉麻醉下扁桃体和腺样体术后的急性躁动。

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	曹立群
	王进飞
	杜化娟
	龚丽娜

关键词 ：小儿, 右美托咪定, 全凭静脉麻醉, 腺样体扁桃体切除术, 术后躁动

Abstract：Objective To observe the effect of Dexmedetomidine on postoperative emergence agitation in the children undergoing tonsillectomy and adenoidectomy with total intravenous anesthesia.Methods Sixty children with total intravenous anesthesia who underwent tonsillectomy and adenoidectomy in Mentougou District Hospital from February 2014 to February 2016 were selected as the research objects.They were divided into Dexmedetomidine group(n=30)and control group(n=30)according to the random number table method.Patients in the Dexmedetomidine group received intravenous Dexmedetomidine 0.5μg/(kg·h),and patients in the control group received saline.The anesthesia time and recovery time of the two groups were recorded.The scores of children′s and infants′postoperative pain scale(CHIPPS)and pediatric anesthesia emergence delirium scale(PAED)were compared between the two groups at the time of recovery and 15,30min after recovery.At the same time,the incidence of nausea and vomiting was observed and compared between the two groups.The incidence rates of CHIPPS score＞3 points and PAED score＞12 points were recorded between the two groups.Results The CHIPPS scores of children in Dexmedetomidine group at the time of recovery and 15,30 min after recovery were lower than those in the control group,and the differences were statistically significant(P＜0.05).The PEAD scores of children in Dexmedetomidine group at the time of recovery and 15,30min after recovery were lower than those of the control group,and the differences were statistically significant(P＜0.05).There were no statistically significant differences between the two groups in the time of anesthesia,the incidence of nausea and vomiting during awaking,the incidence of CHIPPS score＞3 points and the incidence of PAED score＞12 points(P＞0.05).The recovery time of Dexmedetomidine group was longer than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion Dexmedetomidine can decrease the postoperative emergence agitation in the children undergoing tonsillectomy and adenoidectomy with total intravenous anesthesia.

Key words： Children Dexmedetomidine Total intravenous anesthesia Adenotonsillectomy Postoperative emergence agitation

引用本文:

曹立群; 王进飞; 杜化娟; 龚丽娜. 静脉输注右美托咪定在小儿全凭静脉麻醉术后躁动的应用效果[J]. 中国当代医药, 2020, 27(9): 107-110.
CAO Li-qun; WANG Jin-fei; DU Hua-juan; GONG Li-na. Application effect of intravenous Dexmedetom idine on postoperative emergence agitation in the children with total intravenous anesthesia. 中国当代医药, 2020, 27(9): 107-110.

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http://dangdaiyiyao.com/CN/ 或 http://dangdaiyiyao.com/CN/Y2020/V27/I9/107

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