Abstract：Objective To investigate the changes and clinical significance of serum amylase (AMS), lipase (LPS) and C-reactive protein (CRP) levels in patients with acute pancreatitis (AP).Methods A total of 997 cases of AP patients admitted to our hospital from March 2015 to July 2018 were selected as the AP group, among them, 835 cases were mild and 162 cases were severe.Altogether 1000 cases of healthy subjects who underwent physical examination in our hospital during the same period were selected as the healthy group.The serum AMS, LPS and CRP levels of the two groups were detected and compared.Results The levels of serum AMS, LPS and CRP in the AP group were higher than those in the healthy group, and the differences were statistically significant (P＜0.05).The levels of serum AMS, LPS and CRP of mild and severe patients were higher than those of the healthy group, and the differences were statistically significant (P＜0.05).The levels of serum AMS, LPS and CRP of the severe patients were higher than those of the mild patients, and the differences were statistically significant (P＜0.05).Conclusion The levels of AMS, LPS and CRP of patients with AP are higher.AMS, LPS and CRP can be used as reference indexes in the diagnosis of AP and its severity.
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