Abstract：ObjectiveTo investigate the clinical efficacy of Leuprorelin Acetate pretreatment combined with laparoscopic myomectomy in the treatment of giant uterine fibroids.Methods50 patients with giant uterine fibroids who were treated in our hospital from May 2014 to May 2016 were selected as subjects.According to the order of admission,the patients were divided two groups,30 cases in each group.The conventional group was directly given laparoscopic myomectomy,and the experimental group was given Leuprolide Acetate pretreatment before the surgical treatment.The volume of uterine fibroids were compared in the experimental group before and after the treatment,and the surgical conditions,postoperative recovery,the recurrence rate and the pregnancy rate of the two groups were compared.ResultsThe volume of uterine fibroids in the experimental group after treatment was significantly lower than that before treatment,and the difference was statistically significant(P＜0.05).The intraoperative blood loss in the experimental group was less than that in the conventional group,time of off-bed activity,pelvic drainage time and length of hospital stay in the experimental group were all significantly shorter than those in the conventional group,and the differences were statistically significant(P＜0.05).There was no significant difference between the two groups in recurrence rate and pregnancy rate(P＞0.05).ConclusionThe effect of Leuprolide Acetate combined laparoscopic myomectomy is significant in the treatment of patients with giant uterine fibroids,which is easy to reduce intraoperative blood loss,and shorten the length of hospital stay,and is conducive to early recovery.
廖灿. 醋酸亮丙瑞林预处理联合腹腔镜下子宫肌瘤剔除术治疗巨大子宫肌瘤的效果评价[J]. 中国当代医药, 2017, 24(32): 64-66.
LIAO Can. Evaluation on the efficacy of Leuprorelin Acetate pretreatment combined with laparoscopic myomectomy in the treatment of giant uterine fibroids. 中国当代医药, 2017, 24(32): 64-66.
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