Abstract：Objective To observe the effect of Haiao Oral Biofilm in the operation of oral lichen planus (OLP)，and provide reference for the clinical treatment. Methods A total of 26 cases of OLP diagnosed clinically in Oral and Maxillofacial Surgery of Zigong First People′s Hospital in Sichuan From February 2013 to June 2015 were selected as the subjects. The diseased tissues were excised surgically and covered with Haiao Oral Biofilm, and then fixed to the wound by reverse bandage, finally biofilm and the wound were healed naturally. The Chinese version of chronic oral mucosal diseases questionnaire (COMDQ) were filled in the 26 cases, then the scale score of preoperative, one month after the operation, 6 months after the operation, one year after the operation were analysed and compared. Results Haiao Oral Biofilm and wound completely healed naturally, the effective percentage was over 95%. The total scores of the COMDQ 1 and 6 months after the operation, one year after the operation were lower than those preoperative, the differences were statistically significant (P＜0.05). Conclusion Haiao Oral Biofilm can relieve postoperative pain and the changes of social and emotional factors. So it is worthy of clinical application.
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