Abstract:ObjectiveTo investigate the effect of Thalidomide Tablets combined with Tripterygium Glycosides tablets treating oral lichen planus.Methods108 patients with oral lichen planus admitted into periodontics&oral department from September 2014 to October 2016 were selected as study object and they were divided into the routine group(injected with Triamcinolone Acetonide locally)and observation group(treated with the drugs of Thalidomide combined with Tripterygium)according to the end of single or double numbers of visiting numbers and there were 54 cases in each group.The treatment effect,pain and erosion score and incidence of adverse reactions were compared between the two groups.ResultsThe effective rate of the observation group was 96.3%,which was higher than that of the control group (87.0%)(P<0.05).There was no significant difference in pain and erosion score between the groups on admission(P>0.05), and the score of pain and erosion in the observation group were lower than those in the control group (P<0.05).The incidence of adverse reactions in the observation group was 7.4%,which was lower than that of the control group (16.7%) (P<0.05).ConclusionThe effect of Thalidomide Tablets combined with Tripterygium Glycosides tablets is better in the treatment of oral lichen planus.
Cafaro A,Arduino PG,Massolini G,et al.Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus:a prospective case series[J].Laser Med Sci,2014,29(1):185-190.
Sobaniec S,Bernaczyk P,Pietruski J,et al.Clinical assessment of the efficacy of photodynamic therapy in the treatment of oral lichen planus[J].Laser Med Sci,2013,28(1):311-316.