Objective To explore the effect of Salmeterol Fluticasone Propionate in the treatment of bronchial asthma.Methods A total of 103 patients with bronchial asthma admitted to our hospital from March 2017 to November 2018 were selected as the study objects,and they were divided into control group (51 cases) and observation group (52 cases)according to the random number table method.The control group was treated with Salmeterol Hydroxynaphthoate Powder for Inhalation combined with Fluticasone Propionate Inhaled Aerosol,and the observation group was treated with Salmeterol Fluticasone Propionate.The therapeutic effect,pulmonary function (forced expiratory volume in the first second [FEV1),ratio of FEV1 occupational forced vital capacity [FVC][FEV1/FVC],peak expiratory flow [PEF]) and maximum peak expiratory flow rate in the morning (PEFam) before and after treatment were compared in the two groups.Results There were no significant differences in FEV1,FEV1/FVC and PEF between the two groups before treatment(P>0.05).The FEV1,FEV1/FVC and PEF of the two groups after treatment were higher than those before treatment,and the differences were statistically significant (P<0.05).The FEV1,FEV1/FVC and PEF of the observation group after treatment were higher than those of the control group,and the differences were statistically significant (P<0.05).There was no significant difference in PEFam between the two groups before treatment (P>0.05).The PEFam at the first,second,third,and fourth weeks after treatment in both groups were significantly higher than those before treatment,and the differences were statistically significant (P<0.05).The PEFam at the first,second,third,and fourth weeks after treatment in the observation group were significantly higher than those in the control group,and the differences were statistically significant (P<0.05).The total effective rate of the treatment in the observation group was 94.23%,which was significantly higher than that in the control group (84.31%),and the difference was statistically significant (P<0.05).Conclusion The use of Salmeterol Fluticasone Propionate in the treatment of bronchial asthma can effectively improve the pulmonary function of patients,increase the flow rate of the exhalation,relieve clinical symptoms,and the treatment effect is more obvious.