Abstract：Objective To explore the effect of two different radical gastrectomy on the intestinal barrier function of the patients.Methods All of 80 cases were selected from January 2012 to December 2017 in our hospital and medicine from gastric cancer patients,divided into laparotomy group according to the different surgical methods(40 cases)and laparoscopic group(40 cases),the operation time,with intestinal function recovery time,recovery time of bowel sounds,the first exhaust time.were compared between twu groups.Results The operative time of laparoscopic group was significantly longer than that in the laparotomy group,the difference was statistically significant(P＜0.05）;laparoscopic group the intestinal function recovery time,recovery time of bowel sounds,the first exhaust time,first defecation time,eating time and postoperative nausea and vomiting symptom duration was shorter than that in the laparotomy group,the differences were statistically significant (P ＜0.05）.3 and 5 d after operation,the DAO level and D-lactic acid level in the laparoscopic group were lower than those in the laparotomy group(P＜0.05）.There was no significant difference in DAO level and D-lactate level between the two groups after 7 d,and the differences were not statistically significant(P＞0.05）.Conclusions Radical resection of gastric cancer will cause some interference on the intestinal barrier function of patients,including laparoscopic surgery on patients with intestinal barrier interference,postoperative recovery of intestinal barrier function rapidly,although laparoscopic surgery time is too long,but with faster postoperative recovery,has broad application value.
刘鹏 ；佘小琛. 胃癌不同术式对肠道屏障功能的影响对比[J]. 中国当代医药, 2018, 25(14): 75-78.
LIU Peng ；SHE Xiao-chen. Comparison of the effects of different surgical methods on the intestinal barrier function of gastric cancer. 中国当代医药, 2018, 25(14): 75-78.
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