Abstract:Objective To explore the clinical effect of Kang′ai injection combining with chemotherapy on treating breast cancer.Methods From February 2012 to February 2015,50 patients with breast cancer admitted into our hospital were selected,and evenly divided into two groups based on the sequence of admission to hospital.In observation group,Kang′ai injection combining with cyclophosphamide-epirubicin-fluorouracil(CEF)in sequence and docetaxel for chemotherapy was provided,while in control group,only CEF in sequence and docetaxel was used.The clinical therapeutic effect and quality of life(QOL)in both groups were compared.Results There was no great difference in total therapeutic effective rate in both groups as well as clinical effect in inter-group comparisons(P>0.05).The effective rate of QOL in the observation group was 96.00%,much higher than 60.00%in the control group with statistical difference(P<0.05).In the observation group,the incidence of adverse drug reaction (ADR)was 24.00%,greatly lower than 60.00%in the control group with statistical difference(P<0.05).Conclusion Combination of Kang′ai injection with chemotherapy can obtain a remarkable effect in breast cancer patients after surgeries.It can alleviate the adverse reactions caused by chemotherapy drugs and reduce the leukopenia,which is safe and effective,and it is worthy of clinical promotion.
陈凤舞. 康艾注射液联合多西他塞序贯CEF方案化疗治疗乳腺癌的临床研究[J]. 中国当代医药, 2016, 23(22): 106-108.
CHEN Feng-wu. Clinical study of Kang′ai injection combining with CEF in sequence and docetaxel for chemotherapy in the treatment of breast cancer. 中国当代医药, 2016, 23(22): 106-108.