Abstract:Objective To analyze the effect of montelukast in treatment of children with bronchial asthma.Methods Altogether 104 cases of children with bronchial asthma treated in our hospital from April 2013 to August 2015 were randomly and evenly divided into control group and observation group by using the random number table method,with 52 cases in each group.Control group was given conventional treatment,while observation group was treated with montelukast based on treatment in control group.SPSS 17.0 was adopted to make analysis of statistical data,treatment effectiveness and improved pulmonary function between two groups were compared.Results The total effective rate in observation group was 78.8%,significantly higher than 78.8%in control group(P<0.05).Post-treatment forced expiratory volume in one second(FEV1),forced vital capacity(FVC)and forced expiratory flow(FEF)in observation group was(2.9± 0.5)L,(3.0±0.6)L and(6.9±0.8)L/s respectively vs(2.0±0.3)L,(2.5±0.8)L and(5.3±0.9)L/s respectively in control group,the pulmonary function indexes in observation group were significantly better than those of control group (P<0.05).Conclusion Application of montelukast demonstrates its remarkable effectiveness in treatment of bronchial asthma in children.
李秀凤. 孟鲁司特治疗儿童支气管哮喘的效果[J]. 中国当代医药, 2016, 23(19): 128-130.
LI Xiu-feng. Effectiveness of montelukast in treatment of children with bronchial asthma. 中国当代医药, 2016, 23(19): 128-130.