Abstract：Objective To explore the clinical situation of blood fat，blood pressure，blood uric acid （UA），high sensitive C reactive protein（hs-CRP），pancreatic islet function and insulin resistance of new diagnosed with early onset type 2 diabetes patients.M ethods 177 cases of new diagnosed with early onset type 2 diabeteswith complete clinical data in our hospital from January 2014 to December 2015 were selected as the research group，the early-onset group （under 40 years old）was 63 cases，the control group （aged 41-59 years old）was 114 cases.The clinical condition including blood lipid，blood pressure，hepatic and renal function，UA，hs-CRP，pancreatic islet function，and insulin resistance in the two groupswas compared，and whether there was a higher risk of cardiovascular and cerebrovascular risk in new diagnosed with early onset type 2 diabetes was discussed.Results The level of TC，TG，eGFR，UA，hs-CRP，DBP，HOMA-IR in the early-onset group was higher than that in the control group，and the level of the HDL-C in the early-onset group was lower than that in the control group，with significant difference （P＜0.05）.There was no significant difference in the level of LDL-C，Cr，ALT，AST，SBP，fasting blood glucose，HbA1c，glycosylated albumin and HOMA-IS between the two groups （P＞0.05）.The age，waist circumference，BMIvalue in the early-onset group was higher than in the control group，with significant difference（P＜0.05）.Pearson correlation analysis showed that BMIwas positively correlated with TG，HOMA-IR and UA，and negatively correlated with age.TG was positively correlated with TC，hs-CRP，HOMA-IR，DBP，UA，BMI，and negatively correlated with HDL-C.Conclusion The clinical conditions about cardiaovascular risk of newly onset diabetes mellitus are more highly.There are the same important to correct the blood lipid disorder，treatment of hyperuricemia，improvement insulin resistance，antihypertension，as to antihyperglycaemia on new diagnosed with early onset type 2 diabetes to prevent vascular diseases.
林珊珊 ；郭丽敏； 佘其美； 杨雪梅； 田应芳. 新诊断早发2型糖尿病心脑血管疾病风险分析[J]. 中国当代医药, 2016, 23(20): 56-59.
LIN Shan-shan； GUO Li-ming； SHE Qi-mei ；YANG Xue-mei； TIAN Ying-fang. Risk analysis of cardiovascular and cerebrovascular disease in new diagnosed w ith early onset type 2 diabetes. 中国当代医药, 2016, 23(20): 56-59.
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