Abstract：Objective To study the clinical effect of enalapril folic acid in treatment of H type hypertension.Methods 200 patients with H type hypertension in our hospital from February 2013 to November 2015 were selected and divided randomly into routine group（n=100）and compound group（n=100）by sealed envelope non transparent method，patients in the routine group received enalapril treatment，while patients in the compound group received enalapril combined with enalapril folic acid treatment.Total effective rate of H type hypertension，incidence of cardiovascular and cerebrovascular events，difference of homocysteine （Hcy）levels，systolic blood pressure and diastolic blood pressure before and after intervention，difference of quality of life after intervention were compared.Results Total efficiency in the compound group was higher than that in the routine group，the difference was statistically significant（P＜0.01）；Occurrence rate of cardiovascular and cerebrovascular events in the compound group was lower than that in the routine group，the difference was statistically significant（P＜0.01）.Level of Hcy，systolic blood pressure，diastolic blood pressure was similar before intervention，the difference was not significant（P＞0.05）；Above indicators after intervention had significant difference with those before intervention in two groups （P＜0.05）；After intervention，level of Hcy，systolic blood pressure，diastolic blood pressure in the compound group was improved more significantly than that in the routine group respectively，the difference was significant（P＜0.05）.Quality of life in the compound group was significantly better than that in the routine group after intervention，the difference was significant（P＜0.05）.Conclusion Enalapril folic acid in the treatment of H type hypertension can effectively improve the level of blood pressure and Hcy levels，alleviation of clinical symptoms and promote quality of life，which has exact effect and is worthy of promotion.
马国斌;郑伯仁;余碧菁. 依那普利叶酸治疗H型高血压的临床效果分析[J]. 中国当代医药, 2016, 23(22): 40-42.
MA Guo-bin;ZHENG Bo-ren;YU Bi-jing. Clinical effect analysis of enalapril folic acid in treatment of H type hypertension. 中国当代医药, 2016, 23(22): 40-42.
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