Observation of clinical effect of invasivemechanical ventilation combined with Propofol，muscle relaxant in treatment of acutem yocardial infarction and pump failure
LUO Jian-li
Intensive Care Unit，the Fifth People′s Hospital of Foshan City in Guangdong Province，Foshan 528211，China
Abstract：Objective To explore clinical effect of invasive mechanical ventilation combined with Propofol and muscle relaxant in treatment of acute myocardial infarction and pump failure. Methods 48 patients with acute myocardial infarction and pump failure accepted treatments in ICU of our hospital from June 2014 to August 2016 were taken as research objects，24 patients treated with invasivemechanical ventilation combined with Propofol and Atracurium were as observation group，while 24 patients only treated with conventional drugs because some reason as control group.Heart rate，noninvasivemean arterial pressure （MAP），blood gas analysis and other indicators，pulmonary rales and other signs change，left ventricular ejection fraction（LVEF）on 7 days of cardiac ultrasound dynamic graph and average hospitalization time between two groups were compared.Results The illness of patients after treatment in the observation group was significantly improved，and respiratory frequency was slower，heart rate was significantly decreased，pulmonary rales was significantly decreased or disappeared，hypoxemia was quickly corrected，patients in the control group were also improved，but the effectwas significantly lower than that in the observation group（P＜0.05）.Average hospitalization time in the observation group was（20.5±4.9）d，in the control group of（36.6±10.3）d，with a significant difference（P＜0.05）.The incidence of adverse reactions in the observation group was significantly lower than that in the control group （P＜0.05）.Conclusion Effect of invasivemechanical ventilation combined with Propofol，muscle relaxant in treatment of acutemyocardial infarction and pump failure is better than that conventional drug treatment，which it is helpful to improve the survival rate of patients，reduce the average hospitalization time，reduce the economic burden of the patients and the society，thus ithas the promotion significance in clinical treatment.
罗建立. 有创机械通气联合丙泊酚、肌松药治疗急性心梗并泵衰竭的效果观察[J]. 中国当代医药, 2016, 23(28): 47-49.
LUO Jian-li. Observation of clinical effect of invasivemechanical ventilation combined with Propofol，muscle relaxant in treatment of acutem yocardial infarction and pump failure. 中国当代医药, 2016, 23(28): 47-49.
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