Abstract：Objective To explore the clinical effect of Clostridum Butyricum Capsule in treating newborns antibiotic associated diarrhea.Methods 100 newborns with antibiotic associated diarrhea in our hospital from January 2015 to June 2016 were selected as study objects and were divided into observation group and control group by using number table, 50 cases in each group.The control group was used Montmorillonite Powder,the observation group was used Clostridum Butyricum Capsule on the basis of control group.Clinical effect,main symptom improvement time and treatment related adverse reactions in two groups were compared.Results In the observation group,33 cases were markedly effective,effective in 15 cases,ineffective in 2 cases,the total effective rate was 96.0%,which were respectively 21,16,13 and 74.0%in control group,the observation group was obvious better than control group and the difference was significant(χ2=6.414, P＜0.05);stool recovery time,vomiting disappearance time and fever disappearance time in observation group were respectively（3.2±1.0）,（2.1±0.4）and（2.2±0.6）d,which were respectively（5.2±1.5）,（4.6±1.1）and（4.5±1.0）d in control group,and the difference was significant(P＜0.05).No drug related adverse reactions occurred in two groups during treatment.Conclusion Clostridum Butyricum Capsule has exactly effect in treating newborns antibiotic associated diarrhea, which can quickly improve the main clinical symptoms of children,with good safety and is worthy to promotion and application in clinical.
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