Abstract:Objective To compare the application effect of brain multi-slice spiral CT(MSCT)and CT perfusion imaging(CTPI)in evaluation of traumatic diffuse brain swelling(DBS).Methods Altogether 100 cases of patients with DBS from January 2015 to October 2016 were selected as study object.All the patients were scanned by using GE light speed 64-slice spiral CT machine and underwent conventional MSCT and CTPI examinations at 2 to 6 hours after injury and CTPI re-examinations within 72 hours.The detection rate of DBS by using MSCT and CTPI were compared, cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT)and the relationship between ultra clear color images and prognosis of DBS were analyzed.Results The detection rate of DBS by using MSCT was 88.0%, significantly lower than that of CTPI(96.0%)(P<0.01);after treatment,CBF and CBV was increased,while MTT was decreased,the difference of CBF,CBV and MTT between initial examination and reexamination was statistically significant (P<0.01).Conclusion MSCT and CTPI have good application effect in evaluation of DBS,but CTPI can effectively assess the prognosis of patients.By using the color image,disease change can be directly evaluated and observed,which is worthy of clinical application.