Abstract：ObjectiveTo research the curative effect of Simvastatin treatment for chronic obstructive pulmonary disease and its effects on patients with plasma brain natriuretic peptide.Methods180 cases of chronic obstructive pulmonary disease patients were selected as the research object,in the department of respiratory medicine,from October 2015 to April 2016.They were randomly divided into control group and treatment group,90 cases in each group.Two groups of patients were treated with routine,Simvastatin treatment group patients were used;eight months after treatment,two groups of patients were compared before and after treatment in patients with lung function index,dyspnea score index,plasma BNP levels.ResultsAfter 8 months of treatment,two groups of patients with FEV1%and FEV1/FVC levels were significantly better than before treatment （P<0.05）;treatment group patients were found to breathing difficulties questionnaire（mMRC） assessment level was significantly reduced,and the patients in treatment group were found based dyspnea index （BDI） score compared with the control group with significant difference（P<0.05）;treatment group patients were found the BNP level was significantly reduced （P<0.05）.ConclusionSimvastatin combined with routine treatment of chronic obstructive pulmonary disease patients to improve patients′lung function and respiratory difficulty score,can reduce patients BNP,worth clinical promotion.
Global initiative for chronic obstructive lung disease.Global strategy for the diagnosis，management，and prevention of chronic obstructive pulmonary disease 2017 report[EB/OL].（2016-11-16）[2016-12-09].http://www.goldcopd.org.
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