Abstract：Objective To explore the clinical effect of Salvia Miltiorrhizae and Ligustrazine Injection treating cerebral thrombosis.Methods A total of 114 patients with cerebral thrombosis admitted to our hospital from June 2017 to June 2019 were selected as the research subjects.They were divided into control group and observation group according to the random number table method, 57 cases in each group.The control group was treated with conventional western medicine.The observation group was treated with Salvia Miltiorrhizae and Ligustrazine Injection.The traditional Chinese medicine (TCM) syndrome scores before and after treatment, total effective rate of treatment, and superoxide dismutase (SOD), malondialdehyde (MDA), lysophosphatidic acid (LPA), and endothelin (ET) before and after treatment were compared between the two groups.Results The total effective rate of treatment in the observation group (98.25%)was higher than that in the control group (84.21%), and the difference was statistically significant (P＜0.05).TCM syndrome score in the observation group ([8.53±1.24] points) after treatment was lower than that in the control group([12.76±1.61] points), the difference was statistically significant (P＜0.05).After treatment, the SOD content of patients in the observation group ([107.64±14.54] U/ml) was higher than that in the control group ([88.96±12.36] U/ml), MDA([5.56±0.72] μmol/L), LPA ([1.70±0.25] μmol/L), ET ([84.62±6.84] ng/L) content were lower than those in the control group ([7.89±0.94] μmol/L, [2.53±0.33] μmol/L, [120.64±10.51] ng/L), the differences were statistically significant (P＜0.05).Conclusion On the basis of conventional Western medicine treatment for patients with cerebral thrombosis, the treatment with Salvia Miltiorrhizae and Ligustrazine Injection can effectively regulate the patients′ oxidative stress response, and its application effect is significant and worthy of promotion.
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