Abstract：Objective To explore the clinical effect of Edaravone combined with Clopidogrel Hydrogen Sulfate in the treatment of cerebral infarction.Methods A total of 38 patients with cerebral infarction admitted to neurology department of our hospital from January to December 2017 were selected as research objects and according to their admission medical record number，they were divided into observation group （20 cases）and control group （18 cases）by random number table method.Patients in the control group received conventional treatment，like Aspirin，lipid-lowering drugs，and nutrient neuropharmaceuticals and patients in the observation group were treated with Edaravone combined with Clopidogrel Hydrogen Sulfate.One course of treatment was 7 days，with a total of 2 courses of treatment.The total effective rate of clinical treatment，neurological deficit score （NIHSS），viability score （BI），superoxide dismutase （SOD），and malondialdehyde （MAD）levels before and after treatment were compared between the two groups.Results The total effective rate of clinical treatment in the observation group was 90.00%，which was higher than that in the control group （61.11%），and the difference was statistically significant（P＜0.05）.There were no significant differences in NIHSS and BI scores between the two groups before treatment （P＞0.05）.The NIHSS scores of the two groups after treatment were lower than those before treatment，the BI scores were higher than those before treatment，and the differences were statistically significant （P＜0.05）.The NIHSS score of the observation group after treatment was lower than that of the control group，the BI score was higher than that of the control group，and the differences were statistically significant（P＜0.05）.There were no significant differences in the levels of SOD and MAD between the two groups before treatment（P＞0.05）.The SOD levels after treatment in the two groups were higher than those before treatment，the MAD levels were lower than those before treatment，and the differences were statistically significant （P＜0.05）.The level of SOD in the observation group was higher than that in the control group，the MAD level was lower than that in the control group，and the differences were statistically significant （P＜0.05）.Conclusion Edaravone combined with Clopidogrel Hydrogen Sulfate has better therapeutic effect on patients with cerebral infarction.It can effectively restore the patients′nerve function，and regulate SOD and MAD levels to enhance the body′s antioxidant capacity and improve the patients′life ability.
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