Abstract:Objective To explore the effect of different degrees of root canal filling treatment in dental pulp disease Methods The clinical data of 99 patients with endodontic disease who were admitted to our hospital from July 2018 to August 2019 were retrospectively analyzed.According to the difference of filling degree, the patients were divided into exact filling group (n=33), underfilling group (n=33) and overfilling group (n=33).After ten days of treatment, the therapeutic effect, score of pain degree, and quality of life score of the exact filling group, underfilling group, and overfilling group were compared.Results The total effective rate of treatment in the exact filling group was 96.97%, which was significantly higher than the total effective rate of 63.64% in the underfilling group and 66.67% in the overfilling group, and the differences among the three groups were statistically significant (P<0.05).There was no statistically significant difference in the total effective rate between the underfilling group and the overfilling group (P>0.05).After treatment, the visual analogue scale (VAS) score of pain degree in the exact filling group was (2.29±1.00) points, which was lower than that in the underfilling group of (4.60±1.50) points and the overfilling group of (4.51±1.49) points, the differences among the three groups were statistically significant (P<0.05).There was no statistically significant difference in VAS score between the underfilling group and overfilling group (P>0.05).After treatment, the quality of life score in the exact filling group was (89.59±6.82) points, which was higher than that in the underfilling group of (74.71±7.27) points and that in the overfilling group of (75.69±7.62) points, the differences among the three groups were statistically significant (P<0.05).There was no statistically significant difference in the quality of life score between the underfilling group and overfilling group (P>0.05).Conclusion Appropriate root canal filling treatment for patients with dental pulp disease can improve the treatment effect of patients, relieve pain and improve quality of life, and have clinical application value.