Abstract：Objective To analyze the effect of Donepezil combined with Citicoline Sodium Capsule in the treatment of cognitive impairment after stroke.Methods A total of 160 patients with cognitive impairment after stroke admitted to the Department of Neurology of Ganzhou Municipal Hospital from August 2018 to December 2019 were selected as the research objects.They were divided into the control group and the observation group according to the random odd and even number method,with 80 cases in each group.The control group was treated with Donepezil,while the observation group was treated with Donepezil combined with Citicoline Sodium Capsule.The intelligence,cognitive ability,health status,quality of life and total adverse reaction rate of the two groups were compared.Results The cognitive function score and intelligence status score of the observation group after treatment were higher than those of the control group,the difference was statistically significant(P＜0.05).The quality of life score in the observation group after intervention was higher than that in the control group,the difference was statistically significant(P＜0.05).There was no significant difference in the adverse total reaction rate between the two groups (P＞0.05).Conclusion Donepezil combined with Citicoline Sodium Capsule can effectively improve the living ability and neurological function of patients with cognitive impairment after stroke.
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