Abstract：Objective To explore the clinical significance of left ventricular diastolic dysfunction in the treatment of pregnancy-induced hypertension (PIH).Methods Thirty patients with PIH who were treated with Magnesium Sulfate and Nifedipine at Yichun People′s Hospital from February 2018 to May 2020 were selected as research subjects.All patients received ultrasound blood vector flow mapping (VFM) before treatment and 7 days after treatment.The left ventricular diastolic function parameters and left ventricular energy loss (EL) parameters of the left ventricular diastolic phases of PIH before treatment and 7 days after treatment were analyzed.The correlation between EL and left ventricular diastolic function parameters were also analyzed.Results After 7 days of treatment, the late diastolic peak flow rate(A) of the mitral valve, the early mitral valve peak flow rate (E)/early diastolic myocardial velocity (e), isovolumic relaxation time (IRT), peak E deceleration time (EDT), Tei index, and e/late diastolic myocardial velocity (a) were lower than those before treatment.The E/A and e value were higher than those before treatment, and the differences were statistically significant (P＜0.05).There was no statistically significant difference in E value or a value before treatment and 7 days after treatment (P＞0.05).The EL parameters of each phase of the left ventricular diastole after 7 days of treatment were lower than those before treatment with statistical differences (P＜0.05).P4-EL in PIH patients was not correlated with EDT and P1-EL was not with IRT (P＞0.05).P3-EL was negatively correlated with E/A (P＜0.05), and positively correlated with a, e, and E/e (P＜0.05), but was not correlated with e/a (P＞0.05).P5-EL was positively correlated with e,a, A and e/a (P＜0.05), and negatively correlated with E/A (P＜0.05).Conclusion Quantitative evaluation of intracavitary blood flow EL in patients with PIH can evaluate the degree of left ventricular diastolic dysfunction and the effect of treatment.
张卫；袁珍；黄美玲. 评估妊娠高血压治疗中左心室舒张功障碍的临床研究[J]. 中国当代医药, 2021, 28(20): 115-117转121.
ZHANG Wei YUAN Zhen HUANG Mei-ling. Evaluation of the clinical study of left ventricular diastolic dysfunction in the treatment of pregnancy-induced hypertension. 中国当代医药, 2021, 28(20): 115-117转121.
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