Abstract：Objective To explore the efficacy and safety of ultrasound bilateral thoracic transverse muscle plane(TTP)block on reducing postoperative pain in children with cardiac surgery.Methods A total of fifty pediatric patients in the First Affiliated Hospital of Nanjing Medical University from January 2020 to December 2020,and divided into the control group and the TTP group according to the random number table method,with 25 cases in each group.The TTP group received bilateral TTP blocks with 2.5 ml/kg 0.375% Ropivacaine,and the control group received no nerve block.The modified objective pain score (MOPS)in postoperative,the dose of Fentanyl used in interoperatively and postoperative 24 hours,the mechanical ventilation time in postoperative,the ICU stay time,and the length of stay were compared between the two groups,and observed the occurrence of adverse events related with TTP arrest.Results The MOPS of the TTP group was lower than of the control group in postoperative 6,8,12,24 hours,the difference was statistically significant(P＜0.05).The MOPS of the TTP group in postoperative 24 hours was higher than that in postoperative 6 hours in the group,with statistically significant difference (P＜0.05).The dose of Fentanyl used of the TTP group was less than that of the control group in postoperative 24 hours,the mechanical ventilation time in postoperative and the ICU stay time of the TTP group were shorter than those of the control group,with statistically significant differences(P＜0.05).There were no statistically significant differences in the dose of Fentanyl used in interoperatively and the length of stay between the two groups (P＞0.05).None of the children of the TTP group had any adverse events due to TTP block.Conclusion Ultrasound guided bilateral TTP block can be effectively and safely applied to postoperative analgesia in pediatric cardiac surgery,and promote rapid postoperative recovery.
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