Abstract:Objective To explore the effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type.Methods A total of 96 patients with primary hyperlipidemia of Qi stagnation and blood stasis type diagnosed and treated in the department of Neurology clinic of our hospital from January 2017 to November 2019 were selected as the research objects,and they were divided into the control group (48 cases) and the observation group (48 cases) according to the method of random number table methods.Both groups were given diet guidance and lifestyle adjustment.Patients in the control group were given Atorvastatin Calcium tablets orally,The patients in the observation group were given Xuefu Zhuyu Capsules oral capsule on the basis of the treatment in the control group.Both groups were treated for 2 months.The therapeutic effect,the incidence of adverse reactions,the level of blood lipid and the level of traditional Chinese medicine syndrome symptoms before and after treatment of two months were compared between the two groups.Results The total effective rate of the observation group was 95.83%,which was higher than that of the control group (75.00%),the difference was statistically significant(P<0.05).The levels of total cholesterol (TC),triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in the two groups after treatment of two months were lower than those before treatment,and the high density lipoprotein cholesterol (HDL-C) level in the observation group after treatment of two months was higher than that before treatment,the difference was statistically significant (P<0.05).The level of TC,TG and LDL-C in the observation group after treatment of two months were lower than those in the control group,while the level of HDL-C in the observation group after treatment of two months was higher than that in the control group,the difference was statistically significant (P<0.05).The traditional Chinese medicine symptom scores of the two groups after treatment of two months were lower than before treatment,and the score of traditional Chinese medicine symptoms in the observation group after treatment of two months was lower than that in the control group,the difference was statistically significant (P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups (P>0.05).Conclusion The treatment of hyperlipidemia patients of Qi stagnation and blood stasis type with Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets can achieve good clinical effect,which can effectively improve the blood lipid index and traditional Chinese medicine symptoms of patients,and does not increase adverse reactions,it is worthy of clinical promotion and application.
路峰; 白玮炜; 李利峰. 血府逐瘀胶囊联合阿托伐他汀钙片治疗气滞血瘀型高脂血症的效果[J]. 中国当代医药, 2020, 27(14): 75-78.
LU Feng; BAI Wei-wei; LI Li-feng. Effect of Xuefu Zhuyu Capsules combined with Atorvastatin Calcium Tablets in the treatment of hyperlipidemia of Qi stagnation and blood stasis type. 中国当代医药, 2020, 27(14): 75-78.