Abstract:Objective To investigate the role of low dose Dexmetomide in the awakening period of Sevoflurane general anesthesia in children with sleep apnea syndrome surgery.Methods A total of 66 children with sleep apnea syndrome who underwent surgical treatment in our hospital from November 2017 to November 2018 were selected as the research subjects.All children were treated with tonsil adenoidectomy under Sevoflurane inhalation general anesthesia.They were divided into observation group and reference group according to the random number table method, with 33 cases in each group.Children in the reference group were intravenously injected with Ringer′s solution before induction of anesthesia, and children in the observation group were given low dose Dexmedetomidine.The changes of heart rate(HR) and mean arterial pressure (MAP) of the two groups in different periods of anesthesia were compared.The Ramsay sedation score and pediatric anesthesia emergence delirium scale (PAED) score were evaluated, and the incidence of restlessness, the duration of restlessness and the awakening time of anesthesia were recorded in both groups.Results The HR and MAP in the observation group at 10 minutes after injection (T2), awake extubation (T3), and 5 minutes after extubation (T4) were lower than those in the reference group, and the differences were statistically significant (P<0.05).The PAED score and the incidence rate of restlessness in the observation group were lower than those in the reference group, the Ramsay sedation score was higher than that in the reference group, and the duration of restlessness was shorter than that in the reference group, the differences were statistically significant (P<0.05).There was no significant difference in the awakening time of anesthesia between the two groups of children (P>0.05).Conclusion The application of low dose Dexmetomide in children with sleep apnea syndrome during Sevoflurane general anesthesia can maintain better sedation effect, maintain hemodynamic stability, reduce the incidence rate of restlessness during recovery,and has the value of clinical promotion.
任俏. 小剂量右旋美托咪定在睡眠呼吸暂停综合征手术患儿七氟醚全麻苏醒期的作用分析[J]. 中国当代医药, 2020, 27(11): 153-155转159.
REN Qiao. Role analysis of low dose Dexmetomide in the awakening period of Sevoflurane general anesthesia in children with sleep apnea syndrome surgery. 中国当代医药, 2020, 27(11): 153-155转159.