Abstract:Prevention of cardiopulmonary bypass(CPB)coagulation is the key to Heparin-free dialysis in patients with renal failure and high-risk bleeding.A variety of preflushing methods have been carried out to study the factors affecting coagulation during the CPB,in which the anticoagulant effect of traditional Heparin-free dialysis with physiological saline preflushing in vitro has been recognized.With the continuous improvement of preflushing method,Heparin physiological saline is mainly used in the closed circulation preflushing high flux dialyzer to close circulation preflushing dialyzer and tube,so that Heparin fully adsorbs dialysis membrane and tube.Heparinization during CPB can effectively reduce extracorporeal circulation coagulation and the dialysis process does not need normal saline to flush dialyzer and tube.It can not only reduce the blood volume load of patients,but also reduce the workload of nurses and improve the quality of nursing care and the effect of dialysis.The methods of Heparin-free dialysis in the treatment of renal failure with high risk bleeding in recent years are reviewed as follows.
董珍艳; 赵丹凤; 苏伟逸. 无肝素透析治疗肾衰竭并高危出血预冲方法的研究进展[J]. 中国当代医药, 2019, 26(8): 35-37.
DONG Zhen-yan; ZHAO Dan-feng ; SU Wei-yi. Research progress of Heparin-free dialysis pre-flushing method in the treatment of renal failure with high-risk bleeding. 中国当代医药, 2019, 26(8): 35-37.
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