Research progress on the relationship between polycystic ovary syndrome and autoimmune diseases
GU Fang-yun1 GAO Jin-jin2 HOU Li-hui3▲
1.Graduate School of Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China;
2.Heilongjiang U-niversity of Traditional Chinese Medicine,Harbin 150040,China;
3.Department of Obstetrics and Gynecology,the First Hospital Affiliated to Heilongjiang University of Traditional Chinese Medicine,Harbin 150040,China
Abstract：Polycystic ovary syndrome(PCOS)is the most common female endocrine disorders disease,is a common cause of menstrual disorders and infertility in women of childbearing age.Genetic and endocrine factors play a key role in the pathogenesis of PCOS.Low progesterone levels in patients with PCOS lead to overstimulation of the immune system to produce more estrogen,resulting in a variety of autoantibodies.Different antibodies have been found in PCOS patients,for example,antinuclear antibodies(ANA),anti-thyroid antibodies,anti-sperm antibodies,anti-ovarian antibodies,anti-islet cell antibodies,but these antibodies could affect the long-term treatment of these patients,therefore,different levels of antibodies in patients with PCOS have brought new insights into the personalized treatment of diseases.
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