Abstract：Objective The perfusion imaging of"one-stop"multi-modality CT can reflect the abnormal perfusion of cerebral tissue in patients with cerebral infarction,while the CT cerebral angiography can clarify the vascular stenosis or occlusion in head and neck.In this paper,to discussed the value of"one-stop"multi-modal CT in the diagnosis of acute ischemic stroke.Methods A total of 96 patients with acute ischemic stroke within 4.5 to 24 h and admitted to the department of neurology in our hospital from June 2015 to December 2017 were selected as subjects.All participants were confirmed by magnetic resonance-diffusion-weighted imaging (MRI-DWI),but did not receive intravenous thrombolysis or embolectomy.The patients were examined by the"one-stop"multi-modal CT scan of the brain.The parameters of CT perfusion imaging(CTP)were observed and compared,and the relationship between the vascular stenosis and cerebral perfusion abnormality was analyzed by CT perfusion and vascular software.Results ①MRI was taken as the gold standard for acute ischemic stroke.The accuracy of NCCT scan was 39.6%,and the accuracy of multimodal CT was 93.8%.②For 90 patients with abnormal CTP perfusion,there were 38 cases with the ischemic penumbra.Both in the infarct core area and the ischemic penumbra,they had lower values of cerebral blood flow (CBF)in cerebral infarction side than in the contralateral mirrored area,the mean transit time (MTT)and time to peak (TTP)values were longer than the values in the contralateral mirrored area,the cerebral blood volume (CBV)in the infarct core area was significantly lower than that in the infarct mirror area,the differences were statistically significant(P＜0.05).However,for other 52 patients without the ischemic penumbra,values of all parameters except for CBV in cerebral infarction side were significantly different from the values in the contralateral mirrored area (P＜0.05).③CTA could effectively evaluate the degree and location of arterial stenosis,there was a relationship between the abnormal perfusion area and the degree of arterial stenosis(P＜0.05).Conclusion The “one stop” multi-modal CT examination of the brain is simple and rapid.It can demonstrate the hemodynamic changes and the morphology of the vessels in ACI patients,which is conducive to the early diagnosis of acute cerebral infarction,and is more conducive to individualized therapy.
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