Application of pulmonary function tests in patients w ith asthma COPD overlap syndrome and chronic obstructive pulmonary disease
LU Shu-biao1 SHEN Shan-liang2▲ LONG Zhao-hua3 LIN Jing-song4
1.Department of Respiratory,the First People′s Hospital of Shunde District in Foshan City,Guangdong Province,Foshan 528300,China;
2.Departmentof Respiratory,Affiliated Chencun Hospitalof the First People′s Hospitalof Shunde District in Foshan City,Guangdong Province,Foshan 528313,China;
3.Department of Medical Examination,Affiliated Chencun Hospital of the First People′s Hospital of Shunde District in Foshan City,Guangdong Province,Foshan 528313,China;
4.Department of Scientific Education,the First People′s Hospital of Shunde District in Foshan City,Guangdong Province,Foshan 528300,China
Abstract：ObjectiveTo preliminarily describe the differences in the pulmonary function of patients with COPD,asthma-COPD overlap syndrome(ACOS),and to provide a basis for clinical treatment.MethodsFrom December 2015 to December 2016,the First People′s Hospital of Shunde District and Chencun Hospital of the First People′s Hospital of Shunde Districtwere admitted to the outpatient department of 97 patients,themedical records for a series of all stable patients with persistent airflow limitation due to COPD or ACOS were retrospectively reviewed and divided into the COPD group (n=63),ofwhich included 26 patientswithmild tomoderate COPD and 37 patientswith severe COPD,the ACOS group (n=24).All the patients underwent pulmonary function tests,including FVC,FEV1,FEV1/FVC,PEF,MMEF,MVV,airway resistance.ResultsIn pulmonary function,the study found that the PEF of patients in the ACOS group was lower than that of COPD in mild and moderate groups(P＜0.05),but the total respiratory impedance and central airway resistance in the ACOS group was higher than that of COPD patientswith mild tomoderate group(P＜0.01),while the rest the index was not statistically significant(P＞0.05).FVC,FEV1and FEV1/FVC was significantly higher in the ACOS group than that in the COPD severe group(P＜0.05);MMEF and MVV was significantly higher in the ACOSgroup than that in the COPD group(P＜0.01),but there were no significant differences in PEF and respiratory impedance(P＞0.05).PEF,the total respiratory impedance and central airway was higher in the ACOS group than that in the mild to moderate of COPD group (P＜0.05).While the other indexes were not statistically significant(P＞0.05).ConclusionThere are differences in lung function between patients with ACOSand COPD,which provide the basis for clinical treatment.
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