Abstract:Objective To study the clinical curative effect and application value of GM-1 (Monosialotetrahexosyl ganglioside)in treatment of patients with cerebral vascular cognitive impairment.Methods Altogether 86 cases of cerebral vascular cognitive impairment who were treated in our hospital from January 2013 to January 2016 were randomly divided into two groups according to the random number method,43 cases were treated with conventional therapy and classified as control group,while,another 43 patients were treated with GM-1 on the basis of control group and classified as obser-vation group.The clinical efficacy and cognitive function improvement in two groups were compared.Results The total effective rate of observation group was 86.04%,significantly higher than that of control group of 58.13%(P<0.05).The total MMSE score of observation group was(29.04±4.75)points,significantly higher than that of control group of(18.68±4.51)points(P<0.05).Conclusion GM-1 demonstrates has better curative effect in the treatment of cerebral vascular cognitive impairment,and it can improve patients′cognitive function and brain function.
张振平;钟广时;邓裕朋. 单唾液酸四己糖神经节苷脂治疗脑血管病患者认知功能障碍效果观察[J]. 中国当代医药, 2017, 24(5): 128-130.
ZHANG Zhen-ping;ZHONG Guang-shi;DENG Yu-peng. Observation of the effectiveness of GM-1 in treatment of cerebrovascular disease patients with cognitive impairment. 中国当代医药, 2017, 24(5): 128-130.