Abstract:ObjectiveTo investigate the characteristics of ambulatory blood pressure monitoring in patients with hypertension and its relationship with stroke.Methods248 patients with hypertension combined with cerebral stroke treated in our hospital from March 2012 to December 2014 were recruited as the cerebral stroke group,and 173 hypertensive patients without cerebral stroke were selected as the control group.The ambulatory blood pressure monitoring was used in both groups to record the average blood pressure of 24 h,pulse pressure(PP)and so on.ResultsIn the cerebral stroke group,average systolic blood pressure(SBP)of 24 h was(142.47±13.24)mmHg,and PP was(67.10±10.13)mmHg,which were significantly higher than the control group[(131.08±14.16)mmHg and(58.34±9.18)mmHg](P<0.05).Meandiastolic blood pressure(DBP)of 24 h was(76.14±9.47)mmHg in the cerebral stroke group,and was(75.98±9.13)mmHg in the control group,there were no significantly difference between both groups (P>0.05).The circadian SBP respectively were (149.54±10.64)mmHg and(140.24±11.54)mmHg in cerebral stroke group,which were remarkblely higher than those of the control group (138.87±9.86)mmHg and(129.57±10.61)mmHg(P<0.05).DBP at night in cerebral stroke group was(76.04±10.08)mmHg,which was significantly higher than the control group(73.45±9.56)mmHg(P<0.05).The SBP and DBP rhythms were respectively(4.24±0.94)%and(5.53±1.21)%in the cerebral stroke group,which were significantly lower than the control group(9.73±1.32)%and(9.07±1.27)%(P<0.05).ConclusionAverage SBP,PP,circadian SBP and blood pressure circadian rhythm may be relevant to the occurrence of cerebral stroke.Effective control of blood pressure,particularly SBP,may have significant value to reduce the incidence of cerebral stroke.
黄勇慧. 高血压患者血压动态监测特点及与脑卒中的关系[J]. 中国当代医药, 2017, 24(12): 32-34.
HUANG Yong-hui. Characteristics of ambulatory blood pressure monitoring in patients with hypertension and its relationship with stroke. 中国当代医药, 2017, 24(12): 32-34.
Arima H,Chalmers J,Yano Y,et al.The relationship between the morning blood pressure surge and low-grade inflammation on silent cerebral infact and clinical stroke events[J].Atherosclerosis,2011,219(1):316-321.
Shimbo D,Newman JD,Aragaki AK,et al.Association between annual visit-to-visit blood pressure variability and stroke in poetmenopausal women:data from the Women′s Health Initiative[J].Hypertension,2012,60(3):625-630.