Abstract：Objective To explore the effect of Zijin Xiaozhong Lotion treating hemorrhoids pain and the change of visual analog scale (VAS). Methods A total of 60 hemorrhoids patients with external hemorrhoids or mixed hemorrhoids in Shenzhen Anorectal Hospital from August to December 2020 were selected as the research objects. According to the method of drawing lots, they were divided into the observation group and the control group, with 30 cases in each group. The control group was treated with conventional Western medicine symptomatic treatment, and the observation group was treated with conventional western medicine+Zijin Xiaozhong Lotion fumigation combined treatment. VAS pain score, serum interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) levels and adverse reactions were compared between the two groups. Results After treatment, the VAS of the observation group was lower than that of the control group, and the difference was statistically significant (P＜0.05). After treatment, the levels of IL-6, TNF-α and CRP of the observation group were lower than those of the control group, and the differences were statistically significant (P＜0.05). There were no statistically significant differences in the incidence rates of adverse reactions such as infection, edema, wound pain and secondary bleeding between the two groups (P＞0.05). Conclusion Both conventional Western medicine and Zijin Xiaozhong Lotion are effective in the treatment of hemorrhoid pain, but Zijin Xiaozhong Lotion has more obvious inhibitory effect on pain, rapid improvement of inflammatory factors, higher safety and significant clinical application value.
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