Abstract：Objective To explore the effect of quadruple therapy combined with Kangfuxin Liquid in patients with Helicobacter pylori-related ulcer.Methods A total of 56 patients with gastric and duodenal bulb ulcers admitted to the Shangrao Municipal Hospital from March 2018 to March 2020 as the research objects,and divided into the control group and the observation group according to the random number table method,with 28 cases in each group.The control group was treated with quadruple therapy,and the observation group as treated with quadruple therapy combined with Kangfuxin Liquid.The total effective rate, Helicobacter pylori eradication rate and recurrence rate,and total incidence of adverse reactions were compared between the two groups.Results After the treatment,the total effective rate of the observation group was 92.86%,which was higher than 67.87% of the control group,and the differences were statistically significant(P<0.05).The Helicobacter pylori clearance rate of the observation group was 96.43%,which was higher than 71.42% of the control group,and the differences were statistically significant(P<0.05).The recurernce rate of the observation group was 7.14%,which was lower than 28.57% of the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions of the observation group was 7.14%,lower than 28.57% of the control group,and the differences were statistically significant(P<0.05).Conclusion In patients with Helicobacter pylori associated ulcer disease,quadruple therapy combined with Kangfuxin Liquid could significantly improve the clinical efficacy,improve Helicobacter pylori,reduce the recurrence rate of Helicobacter pylori,and effectively reduce the incidence of adverse reactions,and the clinical application value is significant.
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