Abstract：Objective To explore the effect of improved pulmonary rehabilitation training program in patients with above moderate chronic obstructive pulmonary disease (COPD).Methods All of 80 patients with above moderate COPD admitted to the Fifth Affiliated (Zhuhai) Hospital of Zunyi Medical College from July 2016 to July 2018 were divided into the study group (41 cases) and reference group (39 cases) according to the order of treatment.The reference group was given routine treatment and nursing measures + breathing training, and the study group was given a modified pulmonary rehabilitation training program based on the reference group.Both groups were treated for 12 weeks.The distance of 6-minute walk test (6MWT), improved British Medical Research Council Respiratory Questionnaire (mMRC)score, St.George′s Respiratory Questionnaire (SGRQ) score, serum interleukin-6 (IL-6) and tumor necrosis factor-α(TNF-α) levels were compared between the two groups before and after intervention.Results There were no significant differences in the distance of 6MWT, mMRC score, SGRQ score,IL-6 and TNF-α levels between the two groups before intervention (P>0.05).After intervention, the distance of 6MWT of the study group was significantly larger than the reference group, and the mMRC and SGRQ scores were significantly lower than the reference group (P<0.05).The levels of IL-6 and TNF-α in the study group were significantly lower than those in the reference group (P<0.05).Conclusion Applying the improved pulmonary rehabilitation training program in patients with moderate or above COPD can effectively improve their exercise tolerance, relieve symptoms of dyspnea, improve quality of life and inflammatory response of patients.
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