Abstract：ObjectiveTo investigate the value of plasma D-dimer (D-D)and coagulation four markers in pregnant women with pregnancy-induced hypertension syndrome.MethodsA retrospective analysis was carried out on 30 cases of normal pregnant women(the normal pregnancy group),30 cases of non-pregnant women(the normal control group)and 87 cases of pregnant women who were diagnosed as pregnancy-induced hypertension syndrome(the pregnancy-induced hypertension group)in our hospital from January 2015 to June 2016.The level of prothrombin time(PT),activated partial thromboplastin time (APTT),thrombin time (TT),fibrinogen (FIB)and D-D level were compared.ResultsThe PT and APTT of the pregnancy-induced hypertension group was significantly shorter than that of the normal pregnancy group and the normal control group,and the level of FIB and D-D of the pregnancy-induced hypertension group was significantly higher than that of the normal pregnancy group and the normal control group,with significant difference(P＜0.05).The PT and APTT of the normal pregnancy group was significantly shorter than that of the normal control group,and the level of FIB and D-D of the normal pregnancy group was significantly higher than that of the the normal control group,with significant difference (P＜0.05).There was no statistical difference between the TT of the three groups (P＞0.05).ConclusionThe blood of pregnant women is in hypercoagulable state,especially in pregnancy-induced hypertension women.Therefore,the routine examination of blood coagulation and D-D contributes to the understanding the coagulation and fibrinolysis function of pregnancy-induced hypertension women.It has important clinical significance in the diagnosis,observation,treatment and prevention of complications of pregnancy-induced hypertension syndrome.
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