Application comparison of FRD special staining technique and thin-prep cytology test in screening of cervical precancerous lesions
LIU Lu-hui1 LI Gui-bao2▲ WANG Luan-ling1 HUANG Feng-you1 CHEN Xin-mei3 LAI Zhen-miao1 HE Ling-yun4 HU Hong-yun1
1.Xincheng Clinic, People′s Hospital of Yingde City in Guangdong Province, Yingde 513000, China;
2.Division of Science and Education, People′s Hospital of Yingde City in Guangdong Province, Yingde 513000, China;
3.Department of Pathology, People′s Hospital of Yingde City in Guangdong Province, Yingde 513000, China;
4.Department of Gynecology, People′s Hospital of Yingde City in Guangdong Province, Yingde 513000, China
Abstract：Objective To compare the application value of folate receptor-mediated detection(FRD)and thin-prep cytology test(TCT)in cervical cancer screening.Methods By self-control method,from April 2015 to January 2018, 2500 patients in the gynaecological clinic of our hospital performed with FRD and TCT examinations were selected.When the FRD or/and TCT outcomes were positive, the cervical biopsy under colposcope was performed.The biopsy result was set as the golden standard.The positive detection rate of FRD and TCT screening and the diagnostic values of FRD and TCT were evaluated, the parameters were sensitivity, specificity, misdiagnosis rate, missed diagnosis rate, positive predictive rate, and negative predictive rate.Results Among 2500 patients, the positive detection rates of FRD and TCT were 10.32% and 9.96%, respectively, there was no significant difference between the two groups (P＞0.05).With regard to the sensitivity, specificity, misdiagnosis rate, missed diagnosis rate, positive predictive rate and negative predictive rate of the FRD and TCT, there were no significant differences between the two detection methods (P＞0.05).Conclusion FRD and TCT both obtain the effects of screening for cervical precancerous lesions, and the diagnostic value is equivalent.
刘露晖； 李桂宝； 王栾玲； 黄凤友； 陈新妹； 赖珍苗； 贺凌云； 胡红云. FRD特殊染色技术与液基细胞学检查在宫颈癌前病变筛查中的应用对比[J]. 中国当代医药, 2019, 26(18): 31-34.
LIU Lu-hui； LI Gui-bao； WANG Luan-ling； HUANG Feng-you； CHEN Xin-mei； LAI Zhen-miao； HE Ling-yun； HU Hong-yun. Application comparison of FRD special staining technique and thin-prep cytology test in screening of cervical precancerous lesions. 中国当代医药, 2019, 26(18): 31-34.
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