Abstract：Objective To explore the value of colposcopy combined with basal fluid cell monitoring technique in screening cervical precancerous lesions.Methods A total of 9261 patients who underwent cervical/vaginal cytology screening in our hospital from January to August 2018 were enrolled.The specimens were collected and colposcopy and multi-point biopsy were performed on the abnormalities.According to the cervical pathological examination, the coincidence rate between the results of colposcopy combined with basal fluid cell monitoring and pathological examination was calculated.Results There were 9261 cases of cervical cancer screening specimens from basal fluid cytology, in which 8883 cases (95.9%) were in the normal range, and 378 cases (4.1%) were abnormal smears.Among 378 cases of abnormal smears, 189 cases (50.0%) were atypical squamous cells (ASC)+atypical glandular cells (AGC), 119 cases(31.5%) were low-grade lesions in squamous intraepithelial cells (LSIL), 49 cases (13.0%) were high-grade lesion in squamous epithelial cells (HSIL), and 21 cases (5.5%) were squamous cell carcinoma (SCC).The total coincidence rate of colposcopy combined with basal cell positive and pathological examination was 50.0%, among which the diagnostic coincidence rate of ASC+AGC, LSIL, HSIL and SCC was 29.6%, 52.9%, 85.7% and 100.0%, respectively.Under the colposcopy combined with basal fluid cell monitoring, the coincidence rate of ASC+AGC and LSIL with cervical pathology was statistically significant (χ2=8.014, P<0.05).There was no significant difference in the coincidence rate between HSIL and SCC and cervical pathology (χ2=0.875, P>0.05).Conclusion Colposcopy combined with basal fluid cell monitoring technology is a reliable method in screening cervical precancerous lesions, and the coincidence rate with pathological results is high, which can be jointly promoted and applied.
京公网安备 11010502046607号