Advances in the application of Zebrafish as a lung cancer model
YU Hua-lin1 LI Peng-fei2 WANG Li1 DAI Jia-li1 YANG Jin-song1▲
1.Department of Oncology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210,000, China;
2.Department of Ophthalmology, Ophthalmology Hospital Affiliated to Nantong University, Jiangsu Province, Nantong 226000, China
Abstract：Lung cancer is one of the most common human malignancy.Its morbidity and mortality are the highest in the world.Therefore, it is of great significance for the diagnosis and treatment of lung cancer to further understand the related molecular mechanisms and pathogenesis of lung cancer and evaluate the efficacy and safety of anti-lung cancer drugs.And also for the early realization of the countrys security health reform and development of the concept of the people′s livelihood.Zebrafish is a kind of important model organisms.Their genes with human genes are highly conserved, growth speed quick.The most important thing is that early embryonic Zebrafish transparent, which will help the development process for real-time observation.In modern biological research, Zebrafish as a model of human disease are fully applied.This article mainly elaborated the zebrafish in lung cancer research in the field of application and research progress.It′s thought that use Zebrafish lung cancer model construction technology already quite mature.With the continuous development of experimental technology, its application and development in the field of lung cancer related research will make greater progress.
俞华林; 李鹏飞; 汪丽; 戴佳丽; 杨劲松. 斑马鱼作为肺癌模型的应用进展[J]. 中国当代医药, 2019, 26(14): 25-28.
YU Hua-lin; LI Peng-fei; WANG Li; DAI Jia-li; YANG Jin-song. Advances in the application of Zebrafish as a lung cancer model. 中国当代医药, 2019, 26(14): 25-28.
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