Abstract：Objective To study the effect of Sufentanil combined with Remifentanil in anesthesia for emergency brain trauma surgery. Methods Sixty patients with emergency brain trauma received in our hospital from March 2016 to September 2019 were selected as research subjects. They were divided into the reference group and the Sufentanil+Remifentanil group by random number table method. Patients in the reference group (n=30) were anesthetized with Remifentanil alone. In the Sufentanil+Remifentanil group (n=30), Sufentanil combined with Remifentanil for anesthetization was applied. The heart rate (HR), systolic blood pressure (SBP), diastolic blood pressure (DBP) levels, and the blood glucose changes before and after anesthesia between the two groups were compared. Results The HR after 10 min of anesthesia in the reference group was higher than before anesthesia, and the difference was statistically significant(P＜0.05). The levels of SBP and DBP after 10 min of anesthesia in the reference group were lower than before anesthesia, with statistically significant differences (P＜0.05). There was no significant difference in HR, SBP, and DBP before and after 10 min of anesthesia in the Sufentanil+Remifentanil group (P＞0.05). The HR level of patients in the Sufentanil+Remifentanil group was lower than that of the reference group after 10 min of anesthesia, and the difference was statistically significant (P＜0.05). The SBP and DBP levels of patients in the Sufentanil+Remifentanil group were higher than those in the reference group after 10 min of anesthesia, and the differences were statistically significant (P＜0.05).The blood glucose after 10 min of anesthesia in the Sufentanil+Remifentanil group was lower than that of the reference group, and the difference was statistical significance (P＜0.05). Conclusion Sufentanil combined with Remifentanil for anesthetization has a remarkable effect on anesthesia in emergency brain trauma surgery, and can be promoted in clinical practice.
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