Abstract：Objective To investigate the status and risk factors of nosocomial infections in Intensive Care Unit(ICU),and to find effective countermeasures for preventing nosocomial infections.Methods A total of 206 cases of patients treated in ICU from January 2014 to December 2017 were selected as subjects,and the patients that suffered from nosocomial infections were analyzed by retrospective studies.The incidence,location,pathogenic bacteria and influencing factors of infection were observed.The length of stay and hospitalization expenses of patients with and without nosocomial infection were compared.Results Incidence rate of nosocomial infection in ICU was 31.55%,which was significantly higher than that in the whole hospital level(4.29%),and the difference was statistically significant(P<0.05).The average length of hospital stay for patients with nosocomial infections was(40.3±17.1)days,which was longer than that of non-infected patients[(6.5±2.1)d],and the difference was statistically significant(P<0.05).The average hospitalization cost of nosocomial infection patients was(64 379.23±4651.59)yuan,which was significantly higher than that of non-infected patients[(18 245.05±2165.30)yuan],and the difference was statistically significant(P<0.05).The most vulnerable site of nosocomial infections was the lower respiratory tract,which accounted for 58.11%,and patients were mostly infected by Gram-negative bacteria and fungi.Risk factors of nosocomial infections were age(no less than 60 years),long hospitalization time,invasive operation manipulation,massive use of antibiotics and the severe underlying diseases.Conclusion The nosocomial infections in ICU should be treated as focal point.Patients with high risk factors should be given early intervening treatment.Comprehensive intervention strategy should be adopted to reduce the incidence rate of nosocomial infections.
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