Abstract:[Abstract]Objective To explore the clinical effect of Labetalol combined with Magnesium Sulfate in the treatment of hypertensive disorder complicating pregnancy.Methods A total of 50 gestational hypertension patients admitted to our hospital from April 2017 to August 2018 were selected and randomly divided into the control group (25 cases)and the observation group(25 cases).The control group was given Nifedipine combined with Magnesium Sulfate,and the observation group was given Labetalol combined with Magnesium Sulfate.The blood pressure,hemorheology,clinical efficacy and pregnancy outcomes between the two groups were compared.Results The systolic blood pressure and diastolic blood pressure in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).After treatment,the 24 h urine protein,hematocrit and blood viscosity of the observation group were higher than those of the control group,the difference was statistically significant(P<0.05).The total effective rate of treatment in the observation group(92.00%)was significantly higher than that in the control group(64.00%),and the difference was statistically significant(P<0.05).The pregnancy outcome of the observation group was better than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Pregnancy-induced hypertension in pregnant women with Labetalol combined with Magnesium Sulfate can achieve good antihypertensive effect,significantly improve pregnancy outcome.Nifedipine combined with Magnesium Sulfate in the improvement of hemodynamics and renal function is better than Labetalol combined with Magnesium Sulfate.This is worthy of clinical promotion and application.
刘怡雪;周燕;关秀莹. 拉贝洛尔联合硫酸镁治疗妊娠期高血压的临床效果[J]. 中国当代医药, 2019, 26(7): 168-170.
LIU Yi-xue ZHOU Yan GUAN Xiu-ying. Clinical effect of Labetalol combined with Magnesium Sulfate in the treatment of hypertensive disorder complicating pregnancy. 中国当代医药, 2019, 26(7): 168-170.